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Science prediction markets: live odds, ranked by volume

Every market below links to its own page with all outcomes, a price chart and resolution rules. Prices are probabilities: 30¢ means about a 30% chance.

Updated 2026-11-06 01:43 UTC · Source: Polymarket · 18+

AllPoliticsCryptoSportsEconomyBusinessPop cultureScienceGeopoliticsTechElectionsFinance

Markets listed

49
most active by 24h volume

24h volume

$161K
across listed markets

Most active science markets right now

MarketFavoritePrice24h24h volTotal vol
Largest IPO by market cap in 2026?
Climate & Science · IPO · closes January 2, 2027
SpaceX81.5% +10.0$65K$7.6M
Will the US confirm that aliens exist by...?
Aliens · Politics · closes January 1, 2027
December 312.3% -0.1$61K$77.7M
Skin cancer vaccine BLA submitted by...?
FDA · Tech · closes July 1, 2027
June 30, 2027?91.5% +16.0$8K$99K
FDA approves skin cancer vaccine by...?
FDA · Tech · closes January 1, 2028
December 31, 202766.5% -2.0$5K$249K
SpaceX Starship Flight Test 15?
Tech · SpaceX · closes July 1, 2027
November 30, 202694.0% +5.0$5K$66K
Measles cases in U.S. in 2026?
Rewards 20, 4.5, 50 · Climate & Science · closes January 1, 2027
↑5.5k97.5% +0.1$4K$8.3M
OpenAI announces another Millennium Prize solution by...?
AI · Math · closes January 1, 2028
December 31, 202755.5% -1.0$3K$1.2M
Will CMI declare a Millennium Prize Problem solved by ___?
Culture · Science · closes January 1, 2029
December 31, 202828.5% -8.0$2K$471K
New pandemic in 2026?
Pandemics · Climate & Science · closes January 1, 2027
Yes1.8% -0.1$2K$1.3M
Russia pneumonic plague spreads abroad?
Plague · Russia · closes January 1, 2027
Yes2.2% -0.5$1K$136K
Will the Doge-1 Lunar Mission launch by...?
Culture · SpaceX · closes January 1, 2028
December 31, 202718.0% +3.5$1K$1.2M
How many more Millennium Prize Problems will AI solve in 2026?
AI · Math · closes January 1, 2027
079.5% -1.0$919$458K
Precipitation in Hong Kong in November?
Science · Weather · closes February 8, 2027
60-95mm30.0% -4.5$537$2K
AI lab announces another Millennium Prize solution by...?
AI · Math · closes January 1, 2028
December 31, 202767.0% 0.0$485$537K
How many West Nile neuroinvasive disease cases will be reported among New York City residents in 2026?
Science · Weather · closes April 1, 2027
20 to 3476.0% +1.9$302$90K
Precipitation in Seattle in November?
Science · Weather · closes February 8, 2027
5-5.75"31.0% +11.0$269$1K
Precipitation in London in November?
Science · Weather · closes February 8, 2027
100mm+24.0% -12.0$240$2K
Exponential Time Hypothesis disproof confirmed by...?
AI · Math · closes July 1, 2027
June 3091.0% +0.5$236$24K
Plague case in US by December 31?
Plague · health · closes January 1, 2027
Yes2.7% -0.7$224$17K
Which math problems will AI solve in 2026?
AI · Math · closes January 1, 2027
Ramsey Number R(5,5)24.5% 0.0$209$67K
Further substantive progress on the Riemann Hypothesis by ___?
AI · Math · closes January 1, 2027
December 31, 202611.5% +6.0$169$24K
How many US births in 2026?
Culture · Economy · closes May 1, 2027
3.56M–3.59M40.5% +1.5$121$17K
Precipitation in Seoul in November?
Science · Weather · closes February 8, 2027
30-45mm27.0% -25.0$120$874
Measles cases in U.S. by November 30?
Measles · Science · closes December 1, 2026
5600+83.5% +4.0$109$3K
Will CMI declare the Navier-Stokes problem solved by ___?
AI · Math · closes January 1, 2029
December 31, 202837.5% -2.0$97$31K
PHIVOLCS raises Mayon to Alert Level 4 by...?
Science · Weather · closes December 1, 2026
November 30, 202649.0% +15.0$47$847
FDA approves Retatrutide this year?
Science · FDA · closes January 1, 2027
Yes2.4% -0.1$36$598K
How many SpaceX launches in 2026?
Rewards 50, 4.5, 100 Deprec · Recurring · closes January 1, 2027
140-15975.6% +1.4$33$346K
Screwworm National Emergency declared by...?
Science · Pandemics · closes January 1, 2027
December 3113.5% 0.0$26$15K
SpaceX Starship fully reusable before 2027?
Elon Musk · Tech · closes January 1, 2027
Yes33.5% +4.0$25$124K
How many SpaceX launches in November 2026?
Tech · SpaceX · closes December 1, 2026
<1394.0% +0.5$21$932
November 2026 1st, 2nd, or 3rd hottest on record?
Science · Weather · closes December 29, 2026
1st hottest94.0% +1.0$20$11K
Marathon Fusion's high-rate gold alchemy confirmed by...?
Gold · Tech · closes July 1, 2027
June 3026.5% +0.5$20$42K
US Birth Rate in 2026? (Per 1000 Women)
Culture · Economy · closes May 1, 2027
51.0+90.0% 0.0$7$8K
SpaceX Starship fully reusable before 2028?
Business · Tech · closes January 1, 2028
Yes77.0% 0.0$5$1K
Precipitation in NYC in November?
Science · Weather · closes February 8, 2027
2-3"44.0% -0.5$0$754
OpenAI retracts Navier-Stokes solution in 2026?
AI · Math · closes January 1, 2027
Yes6.0% -1.0$0$88
OpenAI retracts Navier-Stokes solution in 2026?
AI · Math · closes January 1, 2027
Yes6.0% -0.5$0$1K
Which Millennium Prize Problem will AI solve next?
AI · Math · closes January 1, 2028
No solution by Dec 31, 202733.5% 0.0$0$323K
OpenAI vs. Anthropic: First to another Millennium Prize?
AI · Math · closes January 1, 2028
OpenAI53.5% 0.0$0$5K
Anthropic announces a Millennium Prize solution by...?
AI · Math · closes January 1, 2028
December 31, 202728.0% 0.0$0$85K
Trump Space Academy begins training by June 30, 2027?
Space · Trump · closes July 1, 2027
Yes10.5% 0.0$0$938
Merck & Moderna merger/acquisition announced in 2026?
M&A · MRK · closes January 1, 2027
Yes45.6% 0.0$0$723
Will CMI declare the Riemann Hypothesis solved by ___?
Culture · Science · closes January 1, 2028
December 31, 202710.5% 0.0$0$40K
Rocket Lab’s Neutron Rocket Launch by December 31?
Tech · Science · closes January 1, 2027
Yes4.3% -0.3$0$12K
SpaceX or OpenAI higher IPO Market Cap?
Elon Musk · OpenAI · closes January 1, 2028
SpaceX83.6% +2.1$0$13K
New Coronavirus Pandemic in 2026?
Recurring · disease · closes January 1, 2027
Yes1.7% -0.1$0$31K
Will Bitcoin replace SHA-256 before 2027?
quantum · Protocol Upgrade · closes January 1, 2027
Yes1.8% 0.0$0$199K
U.S. enacts AI safety bill before 2027?
AI Regulation · Politics · closes January 1, 2027
Yes9.5% +0.5$0$208K
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Frequently asked questions

What are the most traded science prediction markets today?
As of November 6, 2026 the most active is "Largest IPO by market cap in 2026?" with $65K traded in 24 hours, followed by "Will the US confirm that aliens exist by...?".
How often is this list updated?
Prices and volumes are refreshed every few minutes from the Polymarket API. Each market has its own page with full price history and rules.
Are these odds or probabilities?
Prediction market prices read directly as probabilities: a Yes share at 30¢ implies roughly a 30% chance. Unlike sportsbook odds there is no built-in vig, but spreads and fees still apply.